My Cart
My Cart
Message
Email
order@sanyoubio.com
Email
Tel
+86 21 3368 1627
Tel
Immune Checkpoint Protein
Background
Advantages
Applications
Products
Verification
Background
Immune checkpoint proteins are proteins expressed in immune cells and can maintain immune homeostasis. Their abnormal expression and functional imbalance lead to various diseases, such as tumors and autoimmunity. In recent years, the successive marketing of antibody drugs developed for immune checkpoints, such as PD-1/PD-L1 and CTL-4, has opened the door to immunotherapy. Clinical trials on popular targets such as CD24, B7-H3, and 4-1BB are also in full swing, and new immune checkpoints such as CD161 and TREAM2 have also provided new ideas for immunotherapy.
Advantages
Eukaryotic expression, close to natural
Multi-dimensional quality inspection, activity guarantee
Multiple species coverage, flexible choice
Applications
Antibody Discovery
Affinity Verification
Cell Function Verification
Products
Click to Get Free Sample >>
Coming soon!
Verification
High Purity -SDS-PAGE
Cynomolgus / Rhesus Macaque BTN3A1 / BTF5 / CD277, Fc Tag on SDS-PAGE under reducing (R) condition.
The purity of the protein is greater than 85.
High Purity -SEC-HPLC
The purity Human B7-H1 / PD-L1 / CD274, His Tag is more than 99%
Activity -ELISA
Immobilized Human BTN3A1 / BTF5 / CD277, His Tag, can bind Anti-BTN1A1 Reference Antibody ( ICT-01
), EC50 is 0.00601 μg/ mL.
Activity -FACS
Expression analysis of human BTN3A1 / BTF5 / CD277 on Human BTN3A1 / BTF5 / CD277 HEK293 Cell Line
by FACS
Activity -BLI
Anti-BTN1A1 Reference Antibody（ICT-01） captured on CM5 chip via anti-human IgG Fc antibodies
surface, can bind Human BTN3A1 / BTF5 / CD277, hFc Tag (Cat. PHA275) with an affinity constant of
6.96E-10M as determined in a SPR assay
Social Media
Home
Online Chat