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Comprehensive Partner
for Innovative Drug R&D
Message
Email
order@sanyoubio.com
Email
Tel
+86 21 3368 1627
Tel
Comprehensive Partner
for Innovative Drug R&D

Call+86 21 3368 1627
Or Contact Us

My Cart

Control Antibodies for Antibody-Drug Conjugates (ADCs)
Background
Advantages
Applications
Products
Verification
Background
Antibody-drug conjugate ( ADC) comprises monoclonal antibodies targeting specific antigens and small-molecule cytotoxic drugs through a linker (linker), which has the powerful killing effect of traditional small-molecule chemotherapy and tumor targeting of antibody drugs. It has the advantages of high specificity, low toxicity, and minimum side effects for tumor treatment. ADC drugs need to maximize potency while minimizing non-target toxicity, so optimizing antibodies, linkers, and small molecule drugs and their rational combination is also the core of ADC drug design. Various combinatorial optimization processes require the use of ADC standards.
Advantages
Rich Conjugation Portfolio
The platform has mainstream polyload MMAE, DXD, SN38, etc.
Multidimensional Quality Inspection
SDS > 95% , SEC > 90% HIC, ELISA, FACS comprehensive verificatioin
Product Availability
50+ products in stock,fast delivery
Applications
According to different project requirements and stages, Sanyou provides ADC standard products of different magnitudes, which can serve all stages of drug research and development.
In vitro Efficacy Evaluation
In vivo Efficacy Evaluation
Pre-toxicology Experiment
Anti-idiotypic Antibody Development
Products
Coming soon!
Verification
Purity :SEC-HPLC
The purity of the Zilovertamab vedotin is greater than 98%.
Purity :HIC-HPLC
The drug-to-antibody ratio (DAR)of the Zilovertamab vedotin is 3.7.
Bioactivity :FACS
Zilovertamab vedotin shows high affifinity activity at the cellular level.
Internalization Assay
Zilovertamab vedotin shows high internalization  activity on HT29 cells.
Cytotoxicity Assay
Zilovertamab vedotin shows high cell killing  activity on HT-29 cells.
In vivo efficacy evaluation
Zilovertamab vedotin shows high tumor killing  ability.
Other Service
Reagent Products
Protein Customization